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. 2016 Jan 4;44(D1):D48-50.
doi: 10.1093/nar/gkv1323. Epub 2015 Dec 10.

The International Nucleotide Sequence Database Collaboration

Affiliations

The International Nucleotide Sequence Database Collaboration

Guy Cochrane et al. Nucleic Acids Res. .

Abstract

The International Nucleotide Sequence Database Collaboration (INSDC; http://www.insdc.org) comprises three global partners committed to capturing, preserving and providing comprehensive public-domain nucleotide sequence information. The INSDC establishes standards, formats and protocols for data and metadata to make it easier for individuals and organisations to submit their nucleotide data reliably to public archives. This work enables the continuous, global exchange of information about living things. Here we present an update of the INSDC in 2015, including data growth and diversification, new standards and requirements by publishers for authors to submit their data to the public archives. The INSDC serves as a model for data sharing in the life sciences.

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Figures

Figure 1.
Figure 1.
Cumulative growth in INSDC. (A) Base pairs (black, 2365.5 trillion) and sequence reads (blue, 17.8 trillion) for INSDC raw data. (B) Base pairs (black 1449 billion) and sequences (blue, 651.5 million) in INSDC assembled/annotated data.

References

    1. Nakamura Y., Cochrane G., Karsch-Mizrachi I., International Nucleotide Sequence Database Collaboration The international nucleotide sequence database collaboration. Nucleic Acids Res. 2013;41:D21–D24. - PMC - PubMed
    1. Leinonen R., Sugawara H., Shumway M., International Nucleotide Sequence Database Collaboration The sequence read archive. Nucleic Acids Res. 2011;39:D19–D21. - PMC - PubMed
    1. Yilmaz P., Kottmann R., Field D., Knight R., Cole J.R., Amaral-Zettler L., Gilbert J.A., Karsch-Mizrachi I., Johnston A., Cochrane G., et al. Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications. Nat. Biotechnol. 2011;29:415–420. - PMC - PubMed
    1. Yilmaz P., Gilbert J.A., Knight R., Amaral-Zettler L., Karsch-Mizrachi I., Cochrane G., Nakamura Y., Sansone S.A., Glöckner F.O., Field D. The genomic standards consortium: bringing standards to life for microbial ecology. ISME J. 2011;5:1565–1567. - PMC - PubMed
    1. Hsi-Yang Fritz M., Leinonen R., Cochrane G., Birney E. Efficient storage of high throughput DNA sequencing data using reference-based compression. Genome Res. 2011;21:734–740. - PMC - PubMed

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