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Review
. 2016 Jan-Feb;8(1):50-2.
doi: 10.1177/1941738115622158.

Pharmacologic Therapies for Pediatric Concussions

Mark E Halstead
Review

Pharmacologic Therapies for Pediatric Concussions

Mark E Halstead. Sports Health. 2016 Jan-Feb.

Abstract

Context: Pediatric concussions are common, and emphasis on correct diagnosis and management is stressed in consensus guidelines. Medications may have a role in management of concussion, but no consensus exists regarding appropriate pharmacologic therapy.

Evidence acquisition: Nonsystematic review.

Study design: Clinical review.

Level of evidence: Level 4.

Results: There is limited evidence for hypertonic saline to improve posttraumatic headache in the emergency department setting. There is essentially no evidence for the use of any other medication in management of pediatric sport-related concussion.

Conclusion: Further research is necessary to determine whether there is benefit to the use of any pharmacotherapy in the management of pediatric-aged athletes with concussions.

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Conflict of interest statement

The author reports no potential conflicts of interest in the development and publication of this article.

References

    1. Barlow KM, Brooks BL, MacMaster FP, et al. A double-blind, placebo-controlled intervention trial of 3 and 10 mg sublingual melatonin for post-concussion syndrome in youths (PLAYGAME): study protocol for a randomized controlled trial. Trials. 2014;15:271. - PMC - PubMed
    1. Bramley H, Heverley S, Lewis MM, Kong L, Rivera R, Silvis M. Demographics and treatment of adolescent posttraumatic headache in a regional concussion clinic. Pediatr Neurol. 2015;52:493-498. - PubMed
    1. Chan S, Kurowski B, Byczkowski T, Timm N. Intravenous migraine therapy in children with posttraumatic headache in the ED. Am J Emerg Med. 2015;33:635-639. - PMC - PubMed
    1. Fisher B, Thomas D, Peterson B. Hypertonic saline lowers raised intracranial pressure in children after head trauma. J Neurosurg Anesthesiol. 1992;4:4-10. - PubMed
    1. Halstead ME, Walter KD; Council on Sports Medicine and Fitness. Sport-related concussion in children and adolescents. Pediatrics. 2010;126:597-615. - PubMed

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