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Case Reports
. 2016 Jan;59(1):48-55.
doi: 10.1111/myc.12421. Epub 2015 Nov 2.

Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis - case report and review of the literature

Dita Ricna  1   2 , Martina Lengerova  1   2   3 , Martina Palackova  1   2 , Marketa Hadrabova  1   2 , Iva Kocmanova  4 , Barbora Weinbergerova  1   2 , Zdenek Pavlovsky  5 , Pavlina Volfova  1 , Jana Bouchnerova  1   2 , Jiri Mayer  1   2   3 , Zdenek Racil  1   2   3
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Case Reports

Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis - case report and review of the literature

Dita Ricna et al. Mycoses. 2016 Jan.

Abstract

Disseminated fusariosis is a life-threatening, invasive, opportunistic infection in immunocompromised patients, especially those with haematological malignancies. The prognosis is poor because these fungi are resistant to many of the available antifungal agents. We present a case of disseminated fusariosis caused by Fusarium proliferatum in a patient with severe aplastic anaemia complicated by a secondary infection of Aspergillus flavus, with a fatal outcome. We also review the documented Fusarium infections in immunocompromised hosts.

Keywords: Fusarium proliferatum; PCR diagnostics; fusariosis; real-time PCR.

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