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Review
. 2016 Mar;113(3):339-45.
doi: 10.1002/jso.24111. Epub 2015 Dec 10.

The importance of surgical margins in melanoma

Cecilia G Ethun  1 , Keith A Delman  1
Affiliations
Review

The importance of surgical margins in melanoma

Cecilia G Ethun et al. J Surg Oncol. 2016 Mar.

Abstract

Optimization of margins to minimize morbidity and maximize local control is critical to the success of surgical management of primary melanomas. This article synthesizes the historical perspectives and key clinical trials that have contributed to the evolution of resection margins for melanoma, focusing on the importance of surgical margins in the context of an era of improvements in systemic therapy and greater use of minimally invasive techniques.

Keywords: Mohs micrographic surgery; guidelines; immunotherapy; prospective trial; wide local excision.

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