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Review
. 2015 Oct;71(4):363-8.
doi: 10.1016/j.mjafi.2015.07.003. Epub 2015 Sep 26.

Genetics of non syndromic hearing loss

M D Venkatesh  1 , Nikhil Moorchung  2 , Bipin Puri  3
Affiliations
Review

Genetics of non syndromic hearing loss

M D Venkatesh et al. Med J Armed Forces India. 2015 Oct.

Abstract

Non Syndromic Hearing Loss is an important cause for hearing loss. One in 1000 newborns have some hearing impairment. Over 400 genetic syndromes have been described. Non Syndromic Hearing Loss (NSHL) can be inherited in an Autosomal Dominant, Autosomal Recessive or a Sex Linked fashion. There are several reasons why genetic testing should be done in cases of NSHL, the main reasons being for genetic screening and for planning treatment. This review describes the genes involved in NSHL and the genetic mechanisms involved in the pathogenesis of the disease.

Keywords: Genetics; Mutations; NSHL.

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