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Review
. 2015 Oct 13:2:44.
doi: 10.3389/fvets.2015.00044. eCollection 2015.

Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut Health

Ryan J Arsenault  1 , Michael H Kogut  2
Affiliations
Review

Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut Health

Ryan J Arsenault et al. Front Vet Sci. .

Abstract

Immunometabolism is a relatively new research perspective, focusing on both metabolism and immunology and the cross-talk between these biological processes. Immunometabolism can be considered from two perspectives; 1) the role that immune cells play in organ metabolism and metabolic disease, and 2) the metabolic processes that occur within immune cells and how they affect overall immunity. The gut may be the prototypical organ of immunometabolism. The gut is the site of nutrient absorption and is a major, if not the major, immune organ. We also describe the integration of kinomics and the species-specific peptide array to the study of the gut. This unique immunometabolic tool combined with the unique immunometabolic nature of the gut provides significant research potential to many animal health applications.

Keywords: animal agriculture; gut health; immunity; immunometabolism; kinome; metabolism.

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