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Review
. 2015 Apr 17;3(4):2325967115579188.
doi: 10.1177/2325967115579188. eCollection 2015 Apr.

Is Operative Treatment of Achilles Tendon Ruptures Superior to Nonoperative Treatment?: A Systematic Review of Overlapping Meta-analyses

Affiliations
Review

Is Operative Treatment of Achilles Tendon Ruptures Superior to Nonoperative Treatment?: A Systematic Review of Overlapping Meta-analyses

Brandon J Erickson et al. Orthop J Sports Med. .

Abstract

Background: Multiple meta-analyses have been published in efforts to determine whether operative or nonoperative treatment of Achilles tendon ruptures affords superior outcomes.

Purpose: To perform a systematic review of overlapping meta-analyses comparing operative and nonoperative treatment of Achilles tendon ruptures to determine which meta-analyses provide the highest level of evidence for treatment recommendations.

Study design: Systematic review; Level of evidence, 3.

Methods: A systematic review of the literature was performed to identify meta-analyses that fit the study inclusion criteria. Data were extracted from these meta-analyses regarding patient outcomes and reruptures. Meta-analysis quality was assessed using the Oxman-Guyatt and QUOROM (Quality of Reporting of Meta-analyses) systems. The Jadad algorithm was applied to determine the meta-analyses with the highest level of evidence.

Results: Nine meta-analyses met the eligibility criteria, with all but 1 study including level 1 evidence. A total of 5842 patients were included. Seven studies found a higher rate of rerupture in the nonoperative group but a higher rate of complications in the operative group. One study found no differences in rerupture or complication rates, and 1 study found surgery decreased rerupture rates only when compared with nonoperative treatment without a functional brace. Three studies also identified an earlier return to work in the operative group. Almost all (8 of 9) of the meta-analyses had Oxman-Guyatt scores >3, indicating no major flaws.

Conclusion: Operative treatment of Achilles tendon ruptures decreases rerupture rates but increases the risk for minor complications when compared with nonoperative treatment. Additionally, surgical treatment may allow earlier return to work.

Keywords: Achilles tendon; complication; nonoperative meta-analysis; rupture.

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Conflict of interest statement

One or more of the authors declared the following potential conflict of interest or source of funding: S.L. receives royalties from SLACK Inc. B.J.C. receives royalties from Arthex, DJO, and Elsevier; is a consultant for Arthrex, Regentis, and Zimmer; owns stock in Carticept and Regentis; and receives research support from Arthex, Medipost, Musculoskeletal Transplant Foundation, National Institutes of Health (NIAMS and NICHD), Zimmer, Athletico, Ossur, Smith & Nephew, and Tournier. B.R.B. receives research support from Arthrex, Conmed Linvatec, DJO, Smith & Nephew, Ossur, and Tornier and receives royalties from SLACK Inc.

Figures

Figure 1.
Figure 1.
PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) flow diagram for inclusion of studies. ACL, anterior cruciate ligament; PRP, platelet-rich plasma.

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