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Review
. 2015 Dec 7;21(45):12735-41.
doi: 10.3748/wjg.v21.i45.12735.

Interval colorectal carcinoma: An unsolved debate

Mark Benedict  1 , Antonio Galvao Neto  1 , Xuchen Zhang  1
Affiliations
Review

Interval colorectal carcinoma: An unsolved debate

Mark Benedict et al. World J Gastroenterol. .

Abstract

Colorectal carcinoma (CRC), as the third most common new cancer diagnosis, poses a significant health risk to the population. Interval CRCs are those that appear after a negative screening test or examination. The development of interval CRCs has been shown to be multifactorial: location of exam-academic institution versus community hospital, experience of the endoscopist, quality of the procedure, age of the patient, flat versus polypoid neoplasia, genetics, hereditary gastrointestinal neoplasia, and most significantly missed or incompletely excised lesions. The rate of interval CRCs has decreased in the last decade, which has been ascribed to an increased understanding of interval disease and technological advances in the screening of high risk individuals. In this article, we aim to review the literature with regard to the multifactorial nature of interval CRCs and provide the most recent developments regarding this important gastrointestinal entity.

Keywords: Colorectal carcinoma; Detection; Interval colorectal carcinoma; Post colonoscopy colorectal cancer; Screening.

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References

    1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer J Clin. 2015;65:5–29. - PubMed
    1. Richter JM, Campbell EJ, Chung DC. Interval colorectal cancer after colonoscopy. Clin Colorectal Cancer. 2015;14:46–51. - PubMed
    1. Allen JI. Quality measures for colonoscopy: where should we be in 2015? Curr Gastroenterol Rep. 2015;17:10. - PubMed
    1. Winawer S, Fletcher R, Rex D, Bond J, Burt R, Ferrucci J, Ganiats T, Levin T, Woolf S, Johnson D, et al. Colorectal cancer screening and surveillance: clinical guidelines and rationale-Update based on new evidence. Gastroenterology. 2003;124:544–560. - PubMed
    1. Short MW, Layton MC, Teer BN, Domagalski JE. Colorectal cancer screening and surveillance. Am Fam Physician. 2015;91:93–100. - PubMed