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Review
. 2016 Mar;25(3):209-16.
doi: 10.1016/j.hlc.2015.06.827. Epub 2015 Jul 15.

Iron Deficiency in Heart Failure: Looking Beyond Anaemia

Christopher C Y Wong  1 , Austin C C Ng  1 , Leonard Kritharides  1 , Andrew P Sindone  2
Affiliations
Review

Iron Deficiency in Heart Failure: Looking Beyond Anaemia

Christopher C Y Wong et al. Heart Lung Circ. 2016 Mar.

Abstract

Iron is an essential micronutrient in many cellular processes. Iron deficiency, with or without anaemia, is common in patients with chronic heart failure. Observational studies have shown iron deficiency to be associated with worse clinical outcomes and mortality. The treatment of iron deficiency in chronic heart failure patients using intravenous iron alone has shown promise in several clinical trials, although further studies which include larger populations and longer follow-up times are needed.

Keywords: Heart failure; Intravenous iron; Iron deficiency.

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