[Raynaud's phenomenon]

Abstract

Raynaud's phenomenon (RP) is characterized by paroxysmal ischemic crisis of the hands and feet provoked by physical or emotional stimuli. The RP's prevalence is estimated between 4 and 5% of the general population, accompanying or not other conditions, or preceding in years the appearance of various connective tissue diseases. We have to consider, in its pathogenesis, alterations in the vascular tone or intraluminal thromboembolic phenomena. The diagnosis is based on the clinical picture since there are no specific tests to detect primary RP. Therapeutic measures include: change in lifestyle, vasodilator drugs and anti-platelet aggregation drugs, plasmapheresis and surgery. Treatment should be individualized.