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Review
. 2015 Dec:15 Suppl 1:26-33.
doi: 10.1111/ggi.12660.

Visit-to-visit blood pressure variability and dementia

Michiaki Nagai  1 , Satoshi Hoshide  2 , Keigo Dote  1 , Kazuomi Kario  2
Affiliations
Review

Visit-to-visit blood pressure variability and dementia

Michiaki Nagai et al. Geriatr Gerontol Int. 2015 Dec.

Abstract

Visit-to-visit blood pressure variability has been shown to be an independent risk factor for stroke and cognitive impairment. However, the underlying mechanisms are not fully understood. Artery remodeling and silent cerebral injury are suggested to be involved in the relationship between visit-to-visit blood pressure variability and cognitive impairment. The present review article summarizes the recent literature on these topics. Here we review visit-to-visit blood pressure variability, artery remodeling, silent cerebral injury and an issue regarding the impact of these components on dementia including Alzheimer's disease.

Keywords: Alzheimer's disease; Hypertension; cognitive impairment; stroke; visit-to-visit blood pressure variability.

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