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. 2016 Jan;22(1):41-5.
doi: 10.1177/1078345815618384.

Characterizing the Burden of Hepatitis C Infection Among Entrants to Pennsylvania State Prisons, 2004 to 2012

Madeline K Mahowald  1 , Sarah Larney  2 , Nickolas D Zaller  3 , Nicholas Scharff  4 , Lynn E Taylor  5 , Curt G Beckwith  5 , Amanda Noska  6 , Josiah D Rich  5 , Timothy P Flanigan  5
Affiliations

Characterizing the Burden of Hepatitis C Infection Among Entrants to Pennsylvania State Prisons, 2004 to 2012

Madeline K Mahowald et al. J Correct Health Care. 2016 Jan.

Abstract

Although hepatitis C (HCV) infection is common among prisoners, relatively few undergo evaluation for treatment. This study reports the prevalence of chronic infection and the genotype distribution among an incarcerated population. HCV antibody testing was provided to adults entering Pennsylvania prisons; confirmatory and genotype testing were offered to those eligible for treatment. Antibody prevalence among 101,727 individuals was 18.1%. Among 7,633 individuals who underwent confirmatory testing, 69.3% had detectable RNA. Among 3,247 individuals who underwent genotype testing, genotype 1 was the most common (76.6%). The rate of chronic infection after HCV exposure is similar to that reported in the community, as is genotype distribution. Correctional facilities provide access to a population with a high disease burden, creating a public health opportunity for evaluation and treatment.

Keywords: chronic hepatitis C infection; correctional health; hepatitis C genotype distribution; prevalence.

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Conflict of interest statement

We have no conflicts of interest to declare.

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References

    1. Allen SA, Spaulding AC, Osei AM, Taylor LE, Cabral AM, Rich JD. Treatment of chronic hepatitis C in a state correctional facility. Ann Intern Med. 2003;138(3):187–190. - PubMed
    1. Chew KW, Allen SA, Taylor LE, Rich JD, Feller E. Treatment outcomes with pegylated interferon and ribavirin for male prisoners with chronic hepatitis C. J Clin Gastroenterol. 2009;43(7):686–691. - PMC - PubMed
    1. Ditah I, Ditah F, Devaki P, Ewelukwa O, Ditah C, Njei B, Charlton M. The Changing Epidemiology of Hepatitis C Virus Infection in the United States: National Health and Nutrition Examination Survey 2001 through 2010. J Hepatol 2013 - PubMed
    1. Glaze LE, Parks E. Correctional populations in the United States, 2010. BJS. 2011 http://bjs.ojp.usdoj.gov/index.cfm.
    1. Kowdley KV, Lawitz E, Poordad F, Cohen DE, Nelson DR, Zeuzem S, Bernstein B. Phase 2b trial of interferon-free therapy for hepatitis C virus genotype 1. N Engl J Med. 2014;370(3):222–232. - PubMed

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