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. 2016 Apr;35(4):457-9.
doi: 10.1097/INF.0000000000001039.

Infliximab as the First Retreatment in Patients with Kawasaki Disease Resistant to Initial Intravenous Immunoglobulin

Youngmin Youn  1 , Jisoo Kim, Young Mi Hong, Sejung Sohn
Affiliations

Infliximab as the First Retreatment in Patients with Kawasaki Disease Resistant to Initial Intravenous Immunoglobulin

Youngmin Youn et al. Pediatr Infect Dis J. 2016 Apr.

Abstract

Forty-three patients with Kawasaki disease who were resistant to initial intravenous immunoglobulin (IVIG) were randomized to receive either a second dose of IVIG (n = 32) or an infliximab (n = 11). With IVIG retreatment 21 patients (65.6%) responded, and with infliximab 10 patients (90.9%) responded. The infliximab group had shorter duration of fever and fewer days of hospitalization. Coronary artery outcomes and adverse events were similar.

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