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. 1989 May;55(5):1305-7.
doi: 10.1128/aem.55.5.1305-1307.1989.

Use of a novel air separation system in a fed-batch fermentative culture of Escherichia coli

R Fass  1 , T R Clem, J Shiloach
Affiliations

Use of a novel air separation system in a fed-batch fermentative culture of Escherichia coli

R Fass et al. Appl Environ Microbiol. 1989 May.

Abstract

A novel air separation system based on permeable membrane gas separation technology was used to cultivate Escherichia coli. The system fulfilled the dissolved oxygen requirements of a culture of E. coli grown on a glucose synthetic medium at a high and constant growth rate of 0.55 h-1. A biomass yield of 45 g (dry weight) per liter was achieved, and no by-product inhibition by acetate or CO2 was observed.

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References

    1. Biotechnol Bioeng. 1976 Jan;18(1):81-94 - PubMed

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