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Clinical Trial
. 1989 May;120(5):661-4.
doi: 10.1111/j.1365-2133.1989.tb01353.x.

A double-blind study of topical 1 alpha,25-dihydroxyvitamin D3 in psoriasis

P C van de Kerkhof  1 , M van Bokhoven, M Zultak, B M Czarnetzki
Affiliations
Clinical Trial

A double-blind study of topical 1 alpha,25-dihydroxyvitamin D3 in psoriasis

P C van de Kerkhof et al. Br J Dermatol. 1989 May.

Abstract

Several open studies with active forms of vitamin D3 have been reported to be effective in the treatment of psoriasis. We report a double-blind study of 1 alpha,25-dihydroxycholecalciferol in psoriasis using 0.5 microgram of active substance applied topically twice daily. In contrast to previous studies, the present investigation does not provide evidence of clinical efficacy for the drug at that dosage and with the vehicle that was used.

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