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Case Reports
. 2015;20(49).
doi: 10.2807/1560-7917.ES.2015.20.49.30085.

Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015

Henrik Hasman  1 , Anette M Hammerum, Frank Hansen, Rene S Hendriksen, Bente Olesen, Yvonne Agersø, Ea Zankari, Pimlapas Leekitcharoenphon, Marc Stegger, Rolf S Kaas, Lina M Cavaco, Dennis S Hansen, Frank M Aarestrup, Robert L Skov
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Free article
Case Reports

Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015

Henrik Hasman et al. Euro Surveill. 2015.
Free article

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Abstract

The plasmid-mediated colistin resistance gene, mcr-1, was detected in an Escherichia coli isolate from a Danish patient with bloodstream infection and in five E. coli isolates from imported chicken meat. One isolate from chicken meat belonged to the epidemic spreading sequence type ST131. In addition to IncI2, an incX4 replicon was found to be linked to mcr-1. This report follows a recent detection of mcr-1 in E. coli from animals, food and humans in China.

Keywords: Denmark; Escherichia coli; antimicrobial resistance; bacterial infections; clinic; healthcare-associated infections; molecular methods; multidrug resistance; surveillance; typing.

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