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. 2015 Nov-Dec;60(6):637.
doi: 10.4103/0019-5154.169160.

Congenital Giant Keratinous Cyst Mimicking Lipoma: Case Report and Review

Samrat Sabhlok  1 , Ketki Kalele  2 , Asmita Phirange  1 , Supriya Kheur  2
Affiliations

Congenital Giant Keratinous Cyst Mimicking Lipoma: Case Report and Review

Samrat Sabhlok et al. Indian J Dermatol. 2015 Nov-Dec.

Abstract

Epidermal cysts represent the most common cutaneous cysts. They arise following a localized inflammation of the hair follicle and occasionally after the implantation of the epithelium, following a trauma or surgery. Conventional epidermal cysts are about 5 cm in diameter; however, rare reports of cysts more than 5 cm are reported in the literature and are referred as "Giant epidermal cysts." Epidermal cysts although common, can mimic other common benign lesions in the head and neck area. A thorough clinico-pathologic investigation is needed to diagnose these cutaneous lesions as they differ in their biologic behavior, treatment, and prognosis. We report a case of a giant epidermoid cyst in the scalp area of a young female patient which mimicked lipoma on clinical, as well as cyotological examination. We also present a brief review of epidermal cysts, their histopathological differential diagnosis, and their malignant transformation.

Keywords: Giant epidermal cyst; histopathology; keratinous cyst; scalp.

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Figures

Figure 1
Figure 1
Large pear-shaped swelling on the scalp
Figure 2
Figure 2
Lesion excised in toto
Figure 3
Figure 3
Extravasated muddy paste on grossing
Figure 4
Figure 4
Scanner view showing cyst lumen
Figure 5
Figure 5
Keratin flecks and squamoid cells
Figure 6
Figure 6
Keratin granuloma
See this image and copyright information in PMC

References

    1. Zuber TJ. Minimal excision technique for epidermoid (sebaceous) cysts. Am Fam Physician. 2002;65:1409. - PubMed
    1. Nicolaides N, Levan NE, Fu HC. The lipid pattern of the wen (keratinous cyst of the skin) J Invest Dermatol. 1968;50:189–94. - PubMed
    1. Mackie RM. Tumours of the skin. In: Rook A, Wilkinson DS, Ebling FJ, editors. Textbook of Dermatology. 4th ed. Vol. 3. St. Louis: Blackwell Mosby Book Distributors; 1986. pp. 2405–6.
    1. Kang SG, Kim CH, Cho HK, Park MY, Lee YJ, Cho MK. Two cases of giant epidermal cyst occurring in the neck. Ann Dermatol. 2011;23(Suppl 1):S135–8. - PMC - PubMed
    1. Huang CC, Ko SF, Huang HY, Ng SH, Lee TY, Lee YW, et al. Epidermal cysts in the superficial soft tissue: Sonographic features with an emphasis on the pseudotestis pattern. J Ultrasound Med. 2011;30:11–7. - PubMed

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