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Case Reports
. 2016 Mar;63(3):1047-9.
doi: 10.1002/hep.28403. Epub 2016 Feb 3.

Febuxostat-induced acute liver injury

Matt Bohm  1 , Raj Vuppalanchi  1 , Naga Chalasani  1 ; Drug-Induced Liver Injury Network (DILIN)
Affiliations
Case Reports

Febuxostat-induced acute liver injury

Matt Bohm et al. Hepatology. 2016 Mar.
No abstract available

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Figures

Figure 1
Figure 1
Schematic representation of exposure, dechallenge, clinical events with trends of serum liver biochemistries during the clinical course and follow up.
Figure 2
Figure 2
Light microscopy with magnification of liver histology with stains. Panel A. Hematoxylin and Eosin (H&E) – 20×: At low power, the biopsy shows hepatocytes with significant ballooning injury. Panel B. H&E – 40×: At high power, the biopsy shows marked cellular and canalicular cholestasis, as well as ballooned hepatocytes. Panel C. CK7 – 20×: The cytokeratin 7 immunohistochemical stain shows mild ductular reaction.
See this image and copyright information in PMC

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References

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