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. 2016 Jun;15(2):197-204.
doi: 10.1177/1534735415622010. Epub 2015 Dec 17.

Effects of High Doses of Vitamin C on Cancer Patients in Singapore: Nine Cases

Yuen Chuen Fong Raymond  1 , Chong Sze Ling Glenda  2 , Lim Kah Meng  3
Affiliations

Effects of High Doses of Vitamin C on Cancer Patients in Singapore: Nine Cases

Yuen Chuen Fong Raymond et al. Integr Cancer Ther. 2016 Jun.

Abstract

Introduction Intravenous high-dose vitamin C therapy is widely used in naturopathic and integrative oncology; however, a study reviewing its effects has never been performed in Singapore. This article serves to document administration of supportive vitamin C therapy for cancer patients in Singapore.

Methods: The clinical response of 9 cancer patients of differing stages to the regular administration of large doses (25-100 g/d) of intravenous vitamin C (IVC; ascorbic acid) is outlined. Tumor pathology and patient health were verified by doctors who do not practice vitamin C treatment.

Results: Cases suggesting survival beyond prognosis, improvement in quality of life, safe coadministration with and improved tolerance of conventional therapy, and deterioration in clinical condition following withdrawal of vitamin C therapy are documented clinically. Some patients experience the Jarisch-Herxheimer reaction-the release of endotoxin from microorganism death resulting in pimples, fever, and body odor-for a few hours after the therapy, but these are resolved quickly with no lasting effects.

Conclusion: Randomized trials of IVC therapy are recommended because it has minimal side effects and has shown promising results.

Keywords: ascorbic acid; cancer; high-dose vitamin C therapy; intravenous vitamin C; nutrition therapy.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

References

    1. Anand P, Kunnumakkara AB, Sundaram C, et al. Cancer is a preventable disease that requires major lifestyle changes. Pharm Res. 2008;25:2097-2116. - PMC - PubMed
    1. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. Cancer statistics, 2007. CA Cancer J Clin. 2007;57:43-66. - PubMed
    1. Eunice Kennedy Shriver National Institute of Child and Human Development. What are the types of birth defects? https://www.nichd.nih.gov/health/topics/birthdefects/conditioninfo/pages.... Accessed December 5, 2015.
    1. Singapore Cancer Registry, ed. Interim Annual Registry Report. Singapore: Singapore Cancer Registry; 2013.
    1. Strong K, Mathers C, Epping-Jordan J, Resnikoff S, Ullrich A. Preventing cancer through tobacco and infection control: how many lives can we save in the next 10 years? Eur J Cancer Prev. 2008;17:153-161. - PubMed

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