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. 2002 Dec;34(6):457-60.
doi: 10.4143/crt.2002.34.6.457.

A Case of Primary Gastric Choriocarcinoma Presenting with Amenorrhea

Seung Hyun Nam, Seock Ah Im, Ki Sun Bae, In Sook Kang, Jung Mi Kwon, Kyung Eun Lee, Hye Sung Moon, Sun Hee Sung, Woon Sup Han, Chu Myong Seong, Soon Nam Lee

A Case of Primary Gastric Choriocarcinoma Presenting with Amenorrhea

Seung Hyun Nam et al. Cancer Res Treat. 2002 Dec.

Abstract

Primary gastric choriocarcinomas are very rare, and their prognosis is extremely poor. A 37-year-old woman presented with amenorrhea, vaginal spotting and severe nausea, which mimicked a pregnancy and gestational trophoblastic disease. The serum level of the beta-subunit of human chorionic gonadotrophin (beta-hCG) was significantly increased. An endoscopic biopsy of the stomach mass showed the features of a choriocarcinoma, with marked anaplasia and necrosis. Immunohistochemical staining for beta-hCG showed positive results in the choriocarcinoma. Chemotherapy for the choriocarcinoma was administered, but she died 8 months following diagnosis.

Keywords: Chemotherapy; Choriocarcinoma; Human chorionic gonadotrophin; Stomach.

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