Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Dec;5(6):457-65.
doi: 10.1055/s-0035-1567838.

The Practical Application of Clinical Prediction Rules: A Commentary Using Case Examples in Surgical Patients with Degenerative Cervical Myelopathy

Affiliations

The Practical Application of Clinical Prediction Rules: A Commentary Using Case Examples in Surgical Patients with Degenerative Cervical Myelopathy

Lindsay Tetreault et al. Global Spine J. 2015 Dec.

Abstract

Study Design Commentary. Objective This commentary aims to discuss the practical applications of a clinical prediction rule (CPR) developed to predict functional status in patients undergoing surgery for the treatment of degenerative cervical myelopathy. Methods Clinical cases from the AOSpine CSM-North America study were used to illustrate the application of a prediction rule in a surgical setting and to highlight how this CPR can be used to ultimately enhance patient care. Results A CPR combines signs and symptoms, patient characteristics, and other predictive factors to estimate disease probability, treatment prognosis, or risk of complications. These tools can influence allocation of health care resources, inform clinical decision making, and guide the design of future research studies. In a surgical setting, CPRs can be used to (1) manage patients' expectations of outcome and, in turn, improve overall satisfaction; (2) facilitate shared decision making between patient and physician; (3) identify strategies to optimize surgical results; and (4) reduce heterogeneity of care and align surgeons' perceptions of outcome with objective evidence. Conclusions Valid and clinically-relevant CPRs have tremendous value in a surgical setting.

Keywords: clinical prediction rule; degenerative cervical myelopathy; functional status; mJOA; managing expectations; outcomes; surgery; validation.

PubMed Disclaimer

Conflict of interest statement

Disclosures Lindsay Tetreault, none David Le, none Pierre Côté, Grants: Ontario Ministry of Finance and Financial Services Commission of Ontario, Canadian Institute of Health Research; Speaking and/or teaching arrangements: National Judicial Institute, European Spine Society, Societe des Medecins Experts du Quebec; Travel expenses: European Spine Society Michael Fehlings, none

Figures

Fig. 1
Fig. 1
Case 2.
Fig. 2
Fig. 2
Case 3.
Fig. 3
Fig. 3
Case 4.

References

    1. Haynes R B, Sackett D L, Guyatt G H, Tugwell P. Philadelphia: Lippincott Williams & Wilkins; 2005. Clinical Epidemiology: How to Do Clinical Practice Research. 3rd ed.
    1. Knaus W A, Draper E A, Wagner D P, Zimmerman J E. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13(10):818–829. - PubMed
    1. Kamath P S Kim W R; Advanced Liver Disease Study Group. The model for end-stage liver disease (MELD) Hepatology 2007453797–805. - PubMed
    1. Tetreault L A, Kopjar B, Vaccaro A. et al.A clinical prediction model to determine outcomes in patients with cervical spondylotic myelopathy undergoing surgical treatment: data from the prospective, multi-center AOSpine North America study. J Bone Joint Surg Am. 2013;95(18):1659–1666. - PubMed
    1. Kalsi-Ryan S, Karadimas S K, Fehlings M G. Cervical spondylotic myelopathy: the clinical phenomenon and the current pathobiology of an increasingly prevalent and devastating disorder. Neuroscientist. 2013;19(4):409–421. - PubMed

LinkOut - more resources