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. 2015 Dec 17;163(7):1808-1808.e1.
doi: 10.1016/j.cell.2015.12.008.

SnapShot: Interferon Signaling

Kwan T Chow  1 , Michael Gale Jr  1
Affiliations
Free article

SnapShot: Interferon Signaling

Kwan T Chow et al. Cell. .
Free article

Abstract

Interferons (IFNs) are crucial cytokines of antimicrobial, antitumor, and immunomodulatory activity. The three types of IFN (I, II, and III) are classified by their receptor specificity and sequence homology. IFNs are produced and secreted by cells in response to specific stimuli. Here, we review the subsequent IFN signaling events occurring through unique receptors leading to regulation of gene expression for modulation of innate and adaptive immunity. To view this SnapShot, open or download the PDF.

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