Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Jul 11;17(13):4917-23.
doi: 10.1093/nar/17.13.4917.

An ARS/silencer binding factor also activates two ribosomal protein genes in yeast

J C Dorsman  1 , M M Doorenbosch, C T Maurer, J H de Winde, W H Mager, R J Planta, L A Grivell
Affiliations
Free PMC article

An ARS/silencer binding factor also activates two ribosomal protein genes in yeast

J C Dorsman et al. Nucleic Acids Res. .
Free PMC article

Abstract

GFI is an abundant yeast DNA-binding protein, capable of binding to both ARS sequences and to the upstream regions of a number of nuclear genes coding for mitochondrial proteins (Dorsman et al., Nucl. Acids Res., 16 [1988] 7287-7301). GFI binding sites conform to the consensus RTCRYN5ACG, an element also present in the binding sites of factors designated SUF and TAF. These factors act as trans-activators of the constitutive transcription of the genes for ribosomal proteins S33 and L3 respectively. We now present evidence that GFI, TAF and SUF are probably the same protein. We speculate that one of the functions of GFI is the adjustment of the expression of a number of gene families to cell growth rate.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1977 Feb;74(2):560-4 - PubMed
    1. EMBO J. 1987 Feb;6(2):461-7 - PubMed
    1. Cell. 1984 Feb;36(2):503-11 - PubMed
    1. Mol Cell Biol. 1984 Nov;4(11):2455-66 - PubMed
    1. Proc Natl Acad Sci U S A. 1985 Jan;82(1):43-7 - PubMed

Publication types