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. 2016 Mar 9;28(10):2024-9.
doi: 10.1002/adma.201504154. Epub 2015 Dec 21.

Multiprotein Printing by Light-Induced Molecular Adsorption

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Multiprotein Printing by Light-Induced Molecular Adsorption

Pierre-Olivier Strale et al. Adv Mater. .

Abstract

Light-induced molecular adsorption of proteins (LIMAP) allows for quantitative sub-micrometer-resolution printing of multiple biomolecules. Surface-bound gradients are patterned within minutes over an entire glass cover-slip. LIMAP is used to perform selective immuno-assays, to dynamically control the adhesion of individual cells, and to achieve hierarchical co-cultures instrumental for tissue engineering.

Keywords: cell co-culture; photopatterning; poly(ethylene glycol); protein micropatterning; single molecules.

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