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Meta-Analysis
. 2015 Dec 10;7(12):10369-87.
doi: 10.3390/nu7125536.

The Metabolic Effects of Oats Intake in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

Qingtao Hou  1 , Yun Li  2 , Ling Li  3 , Gaiping Cheng  4 , Xin Sun  5 , Sheyu Li  6 , Haoming Tian  7
Affiliations
Meta-Analysis

The Metabolic Effects of Oats Intake in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

Qingtao Hou et al. Nutrients. .

Abstract

The present study aimed to comprehensively assess if oats intake is beneficial for diabetic patients. The literature search was conducted in PubMed database up to 23 August 2015. Fourteen controlled trials and two uncontrolled observational studies were included. Compared with the controls, oats intake significantly reduced the concentrations of glycosylated hemoglobin A1c (HbA1c) (MD, -0.42%; 95% CI, -0.61% to -0.23%), fasting blood glucose (FBG) (MD, -0.39 mmol/L; 95% CI, -0.58 to -0.19 mmol/L), total cholesterol (TC) (MD, -0.49 mmol/L; 95% CI, -0.86 to -0.12 mmol/L), low-density lipoprotein cholesterol (LDL-C) (MD, -0.29 mmol/L; 95% CI, -0.48 to -0.09 mmol/L). Oatmeal significantly reduced the acute postprandial glucose and insulin responses compared with the control meal. The present study has revealed a beneficial effect of oats intake on glucose control and lipid profiles in type 2 diabetic patients. Further investigations of oats intake in patients with type 1 diabetes and the safety of oats consumption are required.

Keywords: cholesterol; glycemic control; meta-analysis; oats; systematic review; type 2 diabetes mellitus; β-glucan.

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Figures

Figure 1
Figure 1
Flow diagram for study identification.
Figure 2
Figure 2
Results of the meta-analysis carried out to investigate the effect of oats intake on glycosylated hemoglobin A1c (HbA1c). The changes from baseline (Mean ± SD) between the two groups were compared. MD, mean difference; CI, confidence interval.
Figure 3
Figure 3
Results of the meta-analysis carried out to investigate the effect of oat intake on fasting blood glucose (FBG). The changes from baseline (Mean ± SD) between the two groups were compared. MD, mean difference; CI, confidence interval.
See this image and copyright information in PMC

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