Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 May;52(2):214-21.
doi: 10.1007/s12020-015-0830-4. Epub 2015 Dec 21.

Emerging strategies for managing differentiated thyroid cancers refractory to radioiodine

Stefania Bulotta  1 , Marilena Celano  1 , Giuseppe Costante  1   2 , Diego Russo  3
Affiliations
Review

Emerging strategies for managing differentiated thyroid cancers refractory to radioiodine

Stefania Bulotta et al. Endocrine. 2016 May.

Abstract

Efficient treatment of radio refractory thyroid cancer is still a major challenge. The recent identification of genetic and epigenetic alterations present in almost all differentiated tumors has revealed novel molecular targets, which can hopefully be exploited to create new treatments for these tumors. This review looks briefly at some of the innovative strategies currently being investigated for the treatment the radioiodine-resistant thyroid cancers.

Keywords: Differentiated thyroid cancer; Molecular targets; Nanodevices; Radioiodine; Re-differentiation strategies.

PubMed Disclaimer

References

    1. Eur J Endocrinol. 2015 May;172(5):R215-25 - PubMed
    1. Pharmacol Ther. 2012 Sep;135(3):355-70 - PubMed
    1. J Clin Endocrinol Metab. 2015 May;100(5):E748-56 - PubMed
    1. Endocr Relat Cancer. 2008 Jun;15(2):499-510 - PubMed
    1. Cell. 2014 Oct 23;159(3):676-90 - PubMed

Publication types

MeSH terms

LinkOut - more resources