Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Oct 31;5(4):39-42.
doi: 10.5826/dpc.0504a10. eCollection 2015 Oct.

High-grade squamous intraepithelial lesion of the oral commissure (bowenoid papulosis). A case and review

Erine A Kupetsky  1 , Carlos A Charles  2 , Joan Mones  3
Affiliations

High-grade squamous intraepithelial lesion of the oral commissure (bowenoid papulosis). A case and review

Erine A Kupetsky et al. Dermatol Pract Concept. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Scanning magnification of the lesion on the oral commissure. [Copyright: ©2015 Kupetsky et al.]
Figure 2.
Figure 2.
Higher magnification of the oral lesion. [Copyright: ©2015 Kupetsky et al.]
Figure 3.
Figure 3.
Higher magnification of the slightly verrucous lesion shows hyperplasia with full-thickness atypia of squamous epithelial cells, evidence of loss of polarity, nuclear crowding, nuclear pleomorphism and increased mitotic figures indicative of high-grade squamous intraepithelial lesions. [Copyright: ©2015 Kupetsky et al.]
Figure 4.
Figure 4.
Human papillomavirus in situ hybridization showing positive staining for the high-risk subtypes, 16/18 (red nuclear staining). [Copyright: ©2015 Kupetsky et al.]
Figure 5.
Figure 5.
p16 immunoperoxidase stain shows strong diffuse positive staining of the lower portion of the lesion with individually positive cells extending into the upper reaches of the epithelium (brown staining). [Copyright: ©2015 Kupetsky et al.]
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Wade TR, Kopf AW, Ackerman AB. Bowenoid papulosis of the genitalia. Arch Dermatol. 1979;115(3):306–8. - PubMed
    1. Johnson TM, Saluja A, Fader D, et al. Isolated extragenital bowenoid papulosis of the neck. J Am Acad Dermatol. 1999;41(5 Pt 2):867–70. - PubMed
    1. Olhoffer IH, Davidson D, Longley J, Glusac EJ, Leffell D. Facial bowenoid papulosis secondary to human papillomavirus type 16. Br J Dermatol. 1999;140(4):761–2. - PubMed
    1. Purnell D, Ilchyshyn A, Jenkins D, et al. Isolated human papillomavirus 18-positive extragenital bowenoid papulosis and idiopathic CD4+ lymphocytopenia. Br J Dermatol. 2001;144(3):619–21. - PubMed
    1. Degener AM, Laino L, Pierangeli A, et al. Human papillomavirus-32-positive extragenital Bowenoid papulosis (BP) in a HIV patient with typical genital BP localization. Sex Transm Dis. 2004;31(10):619–22. - PubMed

LinkOut - more resources