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Review
. 2015:2015:974568.
doi: 10.1155/2015/974568. Epub 2015 Nov 26.

Comparison of the Effectiveness of Pars Plana Vitrectomy with and without Internal Limiting Membrane Peeling for Idiopathic Retinal Membrane Removal: A Meta-Analysis

Affiliations
Review

Comparison of the Effectiveness of Pars Plana Vitrectomy with and without Internal Limiting Membrane Peeling for Idiopathic Retinal Membrane Removal: A Meta-Analysis

Hanhan Liu et al. J Ophthalmol. 2015.

Abstract

We conducted a meta-analysis of published retrospective studies and compared the effectiveness of pars plana vitrectomy with and without internal limiting membrane (ILM) peeling for idiopathic epiretinal membrane (IERM). The results revealed that patients in the IERM+ILM peeling group had better BCVA after surgery within 12 months than those in IERM peeling group. But patients in the IERM peeling group showed better BCVA in the 18th month. More retrospective studies or randomized controlled trials are required to investigate and compare the long-term effect of IERM removal with and without ILM peeling.

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Figures

Figure 1
Figure 1
Study selection flowchart.
Figure 2
Figure 2
Visual outcomes of patients who underwent idiopathic retinal membrane peeling (IERM) only and those who underwent IERM + internal limiting membrane peeling. (a) Best-corrected visual acuity ≤6 months after surgery; (b) best-corrected visual acuity between 6 and 12 months after surgery; (c) best-corrected visual acuity in 18th month after surgery; (d) best-corrected visual acuity >6 months after surgery; (e) rate of improvement in visual acuity—by ≥2 Snellen lines; (f) recurrence rate.

References

    1. Zhu X.-F., Peng J.-J., Zou H.-D., et al. Prevalence and risk factors of idiopathic epiretinal membranes in Beixinjing blocks, Shanghai, China. PLoS ONE. 2012;7(12) doi: 10.1371/journal.pone.0051445.e51445 - DOI - PMC - PubMed
    1. Fraser-Bell S., Ying-Lai M., Klein R., Varma R. Prevalence and associations of epiretinal membranes in Latinos: the Los Angeles Latino Eye Study. Investigative Ophthalmology and Visual Science. 2004;45(6):1732–1736. doi: 10.1167/iovs.03-1295. - DOI - PubMed
    1. Yamashita T., Uemura A., Sakamoto T. Intraoperative characteristics of the posterior vitreous cortex in patients with epiretinal membrane. Graefe's Archive for Clinical and Experimental Ophthalmology. 2008;246(3):333–337. doi: 10.1007/s00417-007-0745-8. - DOI - PubMed
    1. Kase S., Saito W., Yokoi M., et al. Expression of glutamine synthetase and cell proliferation in human idiopathic epiretinal membrane. British Journal of Ophthalmology. 2006;90(1):96–98. doi: 10.1136/bjo.2005.078394. - DOI - PMC - PubMed
    1. Gandorfer A., Rohleder M., Kampik A. Epiretinal pathology of vitreomacular traction syndrome. British Journal of Ophthalmology. 2002;86(8):902–909. doi: 10.1136/bjo.86.8.902. - DOI - PMC - PubMed

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