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Review
. 2016 Feb;67(2):238-42.
doi: 10.1161/HYPERTENSIONAHA.115.05024. Epub 2015 Dec 22.

Preeclampsia and Pregnancy-Related Hypertensive Disorders

S Ananth Karumanchi  1 , Joey P Granger  2
Affiliations
Review

Preeclampsia and Pregnancy-Related Hypertensive Disorders

S Ananth Karumanchi et al. Hypertension. 2016 Feb.

Abstract

Our understanding of hypertension during pregnancy and, in particular, preeclampsia has changed dramatically over the last decade. During the last year (2014–2015), several articles published in Hypertension have provided important insights into the pathogenesis of preeclampsia and its related complications.1–38 In addition, Hypertension also published some key research communications that translated important basic science observations into the clinic. Some of these articles are briefly discussed, highlighting their significance to our understanding of the mechanism of the disease, to predict the disease and to treat or prevent hypertension during pregnancy and other preeclampsia-related complications.

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Conflict of interest statement

Conflicts of Interest:

All other authors disclose no conflict.

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References

    1. Amaral LM, Cornelius DC, Harmon A, Moseley J, Martin JN, LaMarca B. 17-hydroxyprogesterone caproate significantly improves clinical characteristics of preeclampsia in the reduced uterine perfusion pressure rat model. Hypertension. 2015;65:225–231. - PMC - PubMed
    1. Brownfoot FC, Tong S, Hannan NJ, Binder NK, Walker SP, Cannon P, Hastie R, Onda K, Haitu'u-Lino TJ. Effects of pravastatin on human placenta, endothelium, and women with severe preeclampsia. Hypertension. 2015;66:687–697. - PubMed
    1. Burwick RM, Easter SR, Dawood HY, Yamamoto HS, Fichorova RN, Feinberg BB. Complement activation and kidney injury molecule-1–associated proximal tubule injury in severe preeclampsia. Hypertension. 2014;64:833–838. - PubMed
    1. Chen M, Dasgupta C, Xiong F, Zhang L. Epigenetic upregulation of large-conductance ca2+-activated k+ channel expression in uterine vascular adaptation to pregnancy. Hypertension. 2014;64:610–618. - PMC - PubMed
    1. Cornelius DC. Copeptin: A new biomarker that is specific for preeclampsia? Hypertension. 2014;64:1189–1191. - PMC - PubMed

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