Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Dec;6(6):693-8.
doi: 10.3978/j.issn.2078-6891.2015.078.

Abdominal metastases from colorectal cancer: intraperitoneal therapy

Hamza Guend  1 , Sunil Patel  1 , Garrett M Nash  1
Affiliations
Review

Abdominal metastases from colorectal cancer: intraperitoneal therapy

Hamza Guend et al. J Gastrointest Oncol. 2015 Dec.

Abstract

Patients with peritoneal metastasis from colorectal cancer represent a distinct subset with regional disease rather than systemic disease. They often have poorer survival outcomes with systemic chemotherapy. Optimal cytoreductive surgery and intraperitoneal chemotherapy (IPC) offers such patients a more directed therapy with improved survival. In this review, we discuss the diagnosis, evaluation and classification, as well as rational for treatment of peritoneal carcinomatosis (PC) secondary to colorectal cancer.

Keywords: Colorectal peritoneal carcinomatosis (PC); cytoreductive surgery; intraperitoneal chemotherapy (IPC).

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest: The authors have no conflicts of interest to declare.

References

    1. van Gestel YR, de Hingh IH, van Herk-Sukel MP, et al. Patterns of metachronous metastases after curative treatment of colorectal cancer. Cancer Epidemiol 2014;38:448-54. - PubMed
    1. Segelman J, Granath F, Holm T, et al. Incidence, prevalence and risk factors for peritoneal carcinomatosis from colorectal cancer. Br J Surg 2012;99:699-705. - PubMed
    1. Chua TC, Liauw W, Chu F, et al. Viewing metastatic colorectal cancer as a curable chronic disease. Am J Clin Oncol 2012;35:77-80. - PubMed
    1. Klaver YL, Simkens LH, Lemmens VE, et al. Outcomes of colorectal cancer patients with peritoneal carcinomatosis treated with chemotherapy with and without targeted therapy. Eur J Surg Oncol 2012;38:617-23. - PubMed
    1. Franko J, Shi Q, Goldman CD, et al. Treatment of colorectal peritoneal carcinomatosis with systemic chemotherapy: a pooled analysis of north central cancer treatment group phase III trials N9741 and N9841. J Clin Oncol 2012;30:263-7. - PMC - PubMed