Are Astrocytes the Pressure-Reservoirs of Lactate in the Brain?
- PMID: 26698916
- DOI: 10.1016/j.cmet.2015.11.001
Are Astrocytes the Pressure-Reservoirs of Lactate in the Brain?
Abstract
The role of lactate in the brain has been controversial. In this issue, Mächler et al. (2015) present data from in vivo experiments suggesting that there is a downward gradient of lactate in the brain. They provide a mechanistic basis for the proposed export of lactate from astrocytes to neurons.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons.Cell Metab. 2016 Jan 12;23(1):94-102. doi: 10.1016/j.cmet.2015.10.010. Epub 2015 Nov 19. Cell Metab. 2016. PMID: 26698914
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