[Bullous dermatosis at distant sites in patients treated with heparin]

Abstract

Since Perrinaud in 2006 first described three patients with hemorrhagic bullae in relation to the use of heparins, numerous cases have been published. Currently, this entity has been established as a clearly defined pathology. We review all reported cases, diagnostic features and features that differentiate it from other skin manifestations caused by heparin having a worse prognosis and requiring a precise identification.

Keywords: Ampollas; Bullae; Heparin; Heparina; Necrosis.