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Review
. 2015;5(3):161-6.
Epub 2015 Jul 20.

The Iran Thalassemia Prevention Program: Success or Failure?

M Hashemieh, H Timori Naghadeh, M Tabrizi Namini, H Neamatzadeh, M Hadipour Dehshal
Review

The Iran Thalassemia Prevention Program: Success or Failure?

M Hashemieh et al. Iran J Ped Hematol Oncol. 2015.

Abstract

Background: Iran is one of the countries located on the "thalassemia belt" and a thalassemia prevention program was approved in our country in 1995. Many different researchers have studied the success of this program with no unanimous findings.

Material and methods: A comprehensive literature search was performed using PubMed, Web of Science, and Google Scholar databases in Farsi and English languages for relevant articles published up to March 2015.

Results: A total of 46 articles regarding thalassemia prevention were identified. After screening the titles and abstracts, 27 articles were excluded because they were the same articles, review articles, and case reports. Finally, 16 articles about the success of the Iranian thalassemia prevention program were selected for the evaluation.

Conclusion: The findings show that the program has been significantly successful in the reduction of the new thalassemia births, though not in a few provinces like Sistan and Baluchestan. The role of the network of genetic labs has been also indispensable in the reduction of the new births. However, there is ambiguity over the impact of the program on the attitude and awareness of people across the country about the prevention of inherited diseases. However, with the success of the Iran thalassemia prevention program, it needs to be modified to be more compatible with the relevant social textures of different provinces.

Keywords: Iran; Prevention Program; Thalassemia Belt.

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Flow chart displaying literature search and study selection
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References

    1. Christopher AF, Kumari A, Chaudhary S, Hora S, Ali Z, Agrawal SC. Unique pattern of mutations in β-thalassemia patents in Western Utar Pradesh. Indian J Hum Genet. 2013;19(2):207–12. - PMC - PubMed
    1. Miri M, Tabrizi Namini M, Hadipour Dehshal M, Sadeghian Varnosfaderan, Ahmadvand A, Yousef Darestani S, Manshadi M. Thalassemia in Iran in Last Twenty Years: the Carrier Rates and the Births Trend. Iranian Journal of Blood and Cancer. 2013;1:11–18.
    1. Abolghasemi H, Amid A, Zeinali S, Radfar MH, Eshghi P, Rahiminejad MS, et al. Thalassemia in Iran: epidemiology, prevention, and management. J Pediatr Hematol Oncol. 2007;29(4):233–8. - PubMed
    1. Samavat A, Modell B. Iranian national thalassaemia screening program. BMJ. 2004;329(7475):1134–1137. - PMC - PubMed
    1. Hadipour Dehshal M, Ahmadvand A, Darestani SY, Manshadi M, Abolghasemi H. Secular trends in the national and provincial births of new thalassemia cases in Iran from 2001 to 2006. Hemoglobin. 2013;37(2):124–37. - PubMed

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