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. 2016 Jan;14(1):23-65.
doi: 10.2450/2015.0172-15. Epub 2015 Dec 15.

Recommendations for the implementation of a Patient Blood Management programme. Application to elective major orthopaedic surgery in adults

Stefania Vaglio  1   2 , Domenico Prisco  3 , Gianni Biancofiore  4 , Daniela Rafanelli  5 , Paola Antonioli  6 , Michele Lisanti  7 , Lorenzo Andreani  7 , Leonardo Basso  8 , Claudio Velati  9 , Giuliano Grazzini  1 , Giancarlo M Liumbruno  1
Affiliations

Recommendations for the implementation of a Patient Blood Management programme. Application to elective major orthopaedic surgery in adults

Stefania Vaglio et al. Blood Transfus. 2016 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Pre-operative flow-chart for patients undergoing elective major orthopaedic surgery and included in a Patient Blood Management programme.
Figure 2
Figure 2
Initial evaluation of bleeding disorders (modified from Liumbruno GM et al., Nichols WL et al.13).
Figure 3
Figure 3
Algorithm for the diagnosis of iron-deficiency anaemia (modified from Muñoz M et al.–19). Hb: haemoglobin; MCH: mean corpuscular haemoglobin; The dashed arrow indicates the need to measure the ferritin level; *: The mean corpuscular volume (MCV) is a relatively late indicator of iron deficiency in patients without active bleeding; in the presence of a low MCV the differential diagnosis from thalassaemia must be made; the MCV can be normal in the presence of vitamin B12 or folate deficiency, post-haemorrhagic reticulocytosis, initial response to oral iron therapy, alcohol intake or myelodysplasia. ** Additional laboratory tests: reticulocyte count; creatinine; C-reactive protein. *** Additional laboratory tests to evaluate the iron deficiency: ratio between soluble transferrin receptor (sTfR) and logarithm of ferritin; hypochromic red blood cells; haemoglobin content in reticulocytes.
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