Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jan;14(1):23-65.
doi: 10.2450/2015.0172-15. Epub 2015 Dec 15.

Recommendations for the implementation of a Patient Blood Management programme. Application to elective major orthopaedic surgery in adults

Stefania Vaglio  1   2 , Domenico Prisco  3 , Gianni Biancofiore  4 , Daniela Rafanelli  5 , Paola Antonioli  6 , Michele Lisanti  7 , Lorenzo Andreani  7 , Leonardo Basso  8 , Claudio Velati  9 , Giuliano Grazzini  1 , Giancarlo M Liumbruno  1
Affiliations

Recommendations for the implementation of a Patient Blood Management programme. Application to elective major orthopaedic surgery in adults

Stefania Vaglio et al. Blood Transfus. 2016 Jan.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Pre-operative flow-chart for patients undergoing elective major orthopaedic surgery and included in a Patient Blood Management programme.
Figure 2
Figure 2
Initial evaluation of bleeding disorders (modified from Liumbruno GM et al., Nichols WL et al.13).
Figure 3
Figure 3
Algorithm for the diagnosis of iron-deficiency anaemia (modified from Muñoz M et al.–19). Hb: haemoglobin; MCH: mean corpuscular haemoglobin; The dashed arrow indicates the need to measure the ferritin level; *: The mean corpuscular volume (MCV) is a relatively late indicator of iron deficiency in patients without active bleeding; in the presence of a low MCV the differential diagnosis from thalassaemia must be made; the MCV can be normal in the presence of vitamin B12 or folate deficiency, post-haemorrhagic reticulocytosis, initial response to oral iron therapy, alcohol intake or myelodysplasia. ** Additional laboratory tests: reticulocyte count; creatinine; C-reactive protein. *** Additional laboratory tests to evaluate the iron deficiency: ratio between soluble transferrin receptor (sTfR) and logarithm of ferritin; hypochromic red blood cells; haemoglobin content in reticulocytes.
See this image and copyright information in PMC

References

    1. Department of Health, Victoria, Australia. Patient Blood Management. [Accessed on 03/12/2014]. Available at: http://www.health.vic.gov.au/bloodmatters/management/index.htm.
    1. Goodnough LT, Shander A. Current status of pharmacologic therapies in patient blood management. Anesth Analg. 2013;116:15–34. - PubMed
    1. Shander A. Introduction. Best Pract Res Clin Anaesthesiol. 2013;27:1–3. - PubMed
    1. Liumbruno GM, Vaglio S, Grazzini G, et al. Patient blood management: a fresh look at a fresh approach to blood transfusion. Minerva Anestesiol. 2015;81:1127–37. - PubMed
    1. Hofmann A, Farmer S, Shander A. Five drivers shifting the paradigm from product-focused transfusion practice to patient blood management. Oncologist. 2011;16(Suppl 3):3–11. - PubMed