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Review
. 2016 Jan;51(1):8-12.
doi: 10.1016/j.jpedsurg.2015.10.022. Epub 2015 Nov 10.

Advances in tissue engineering

Robert Langer  1 , Joseph Vacanti  2
Affiliations
Review

Advances in tissue engineering

Robert Langer et al. J Pediatr Surg. 2016 Jan.

Abstract

Nearly 30 years ago, we reported on a concept now known as Tissue Engineering. Here, we report on some of the advances in this now thriving area of research. In particular, significant advances in tissue engineering of skin, liver, spinal cord, blood vessels, and other areas are discussed.

Keywords: biodegradable materials; regenerative medicine; tissue engineering.

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Figures

Figure 1
Figure 1
Tissue Engineering Schematic
Figure 2
Figure 2
Photolithographic approach to create a vascular bed for tissue engineered liver.
Figure 3
Figure 3
A tiled lobular architecture of a vascular bed micro machined for tissue engineered liver.
See this image and copyright information in PMC

References

    1. Vacanti J, Morse M, Saltzman M, et al. Selective cell transplantation using bioabsorbable artificial polymers as matrices. J Pediatr Surg. 1988;23:3–9. - PubMed
    1. Jaklenec A, Stamp A, Deweerd E, et al. Progress in tissue engineering and stem cell industry “Are we there yet?”. Tissue Eng. 2012;18:155–166. - PubMed
    1. Johnson L, Aiken J, Mooney D, et al. The mesentery as a laminated vascular bed for hepatocyte transplantation. Cell Transplant. 1994;3:273–281. - PubMed
    1. Takeda T, Vacanti J. Hepatocyte transplantation in the Dalmatian dog model of hyperuricosuria. Tissue Eng. 1995;1:355–360. - PubMed
    1. Griffith L, Wu B, Cima M, et al. In vitro organogenesis of liver tissue. Annu NY Acad Sci. 1997;831:382–397. - PubMed

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