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. 2015 Dec 28;60(3):1912-7.
doi: 10.1128/AAC.02756-15.

KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel

A Baraniak  1 , R Izdebski  1 , J Fiett  1 , M Herda  1 , L P G Derde  2 , M J M Bonten  2 , A Adler  3 , Y Carmeli  3 , H Goossens  4 , W Hryniewicz  1 , C Brun-Buisson  5 , M Gniadkowski  6 ; MOSAR WP2, WP3, and WP5 Study Groups
Collaborators, Affiliations

KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel

A Baraniak et al. Antimicrob Agents Chemother. .

Abstract

In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed.

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