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Case Reports
. 2015 Dec;78(4):424-6.

Occult HBV reactivation induced by ibrutinib treatment: a case report

Patrick de Jésus Ngoma, Benoît Kabamba, Geraldine Dahlqvist, Christine Sempoux, Nicolas Lanthier, Tony Shindano, Eric Van Den Neste, Yves Horsmans
  • PMID: 26712054
Free article
Case Reports

Occult HBV reactivation induced by ibrutinib treatment: a case report

Patrick de Jésus Ngoma et al. Acta Gastroenterol Belg. 2015 Dec.
Free article

Abstract

Ibrutinib is a small molecule that has been recently developped for the treatment of B cell malignancies. Common side effects are diarrhoea, nausea, fatigue, infections, neutropenia and thrombocytopenia. Here we report the first case of Hepatitis B virus reactivation in a 80 years old chronic lymphocytic leukaemia patient receiving ibrutinib, suggesting that such treatment must be associated with HBV screening.

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