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Case Reports
. 2016 Mar;58(3):232-234.
doi: 10.1111/ped.12780. Epub 2015 Dec 29.

Thrombocytopenia-associated multi-organ failure caused by diabetic ketoacidosis

Tarek Alsaied  1 , Stuart L Goldstein  2   3 , Ahmad Kaddourah  2 , Sue E Poynter  4
Affiliations
Case Reports

Thrombocytopenia-associated multi-organ failure caused by diabetic ketoacidosis

Tarek Alsaied et al. Pediatr Int. 2016 Mar.

Abstract

Thrombocytopenia-associated multi-organ failure (TAMOF) is an increasingly reported entity in the pediatric intensive care unit. The clinical presentation is similar to thrombotic thrombocytopenic purpura, but with no evidence of hemolysis and no schistocytes on peripheral smear. We report a case of TAMOF induced by diabetic ketoacidosis and treated with therapeutic plasma exchange (TPE). Early diagnosis and initiation of TPE significantly decrease the morbidity associated with TAMOF.

Keywords: diabetes mellitus; diabetic ketoacidosis; multiple organ failure; plasma exchange; thrombocytopenia.

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References

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