Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2015 Dec 29:44:58.
doi: 10.1186/s40463-015-0111-5.

Detection of bacteria in middle ear effusions based on the presence of allergy: does allergy augment bacterial infection in the middle ear?

Woo Jin Kim  1 , Byung-Guk Kim  2 , Ki-Hong Chang  3 , Jeong-Hoon Oh  4   5
Affiliations
Comparative Study

Detection of bacteria in middle ear effusions based on the presence of allergy: does allergy augment bacterial infection in the middle ear?

Woo Jin Kim et al. J Otolaryngol Head Neck Surg. .

Erratum in

Abstract

Background: Bacterial infection, Eustachian tube dysfunction, allergies, and immunologic factors are major causes of otitis media with effusion (OME). However, the exact pathogenesis of OME is still unclear. This study evaluated whether allergy influences bacterial growth in middle ear effusions.

Materials: Fifty-four samples were obtained from OME patients 3-10 years of age who underwent ventilation tube insertion and were divided into two groups based on the presence of allergy as determined using the multiple allergosorbent test (MAST). Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis bacterial DNA in the middle ear effusions was analyzed using polymerase chain reaction. Overall detection rates and those for each species were compared between the two groups.

Results: Of the 54 middle ear effusion samples, 38 (70.4 %) contained bacterial DNA and 14 (36.8 %) of these contained DNA from multiple species. S. pneumoniae was detected in 27 samples (50 %), H. influenzae in 17 samples (31.4 %), and M. catarrhalis in 9 samples (16.6 %). There was no significant difference in the bacterial detection rates between the middle ear effusions of the MAST-positive and MAST-negative groups.

Conclusion: The rate of bacteria detection in middle ear effusions did not differ between allergic and non-allergic children.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
The rates of the overall detection of bacteria and detection of multiple bacteria in middle ear effusion using polymerase chain reaction in MAST-positive and -negative groups (MAST, multiple allergosorbent test)
See this image and copyright information in PMC

References

    1. Kwon C, Lee HY, Kim MG, Boo SH, Yeo SG. Allergic diseases in children with otitis media with effusion. International journal of pediatric otorhinolaryngology. 2013;77(2):158–61. doi: 10.1016/j.ijporl.2012.09.039. - DOI - PubMed
    1. Gok U, Bulut Y, Keles E, Yalcin S, Doymaz MZ. Bacteriological and PCR analysis of clinical material aspirated from otitis media with effusions. International journal of pediatric otorhinolaryngology. 2001;60(1):49–54. doi: 10.1016/S0165-5876(01)00510-9. - DOI - PubMed
    1. Pelikan Z. Role of nasal allergy in chronic secretory otitis media. Current allergy and asthma reports. 2009;9(2):107–13. doi: 10.1007/s11882-009-0016-3. - DOI - PubMed
    1. Kariya S, Okano M, Hattori H, Sugata Y, Matsumoto R, Fukushima K, et al. TH1/TH2 and regulatory cytokines in adults with otitis media with effusion. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2006;27(8):1089–93. doi: 10.1097/01.mao.0000224087.93096.4d. - DOI - PubMed
    1. Lazo-Saenz JG, Galvan-Aguilera AA, Martinez-Ordaz VA, Velasco-Rodriguez VM, Nieves-Renteria A, Rincon-Castaneda C. Eustachian tube dysfunction in allergic rhinitis. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2005;132(4):626–9. doi: 10.1016/j.otohns.2005.01.029. - DOI - PubMed

Publication types

MeSH terms