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Comparative Study
. 2015 Dec 30:13:205.
doi: 10.1186/s12955-015-0401-7.

Anxiety, depression, perceived social support and quality of life in Malaysian breast cancer patients: a 1-year prospective study

Chong Guan Ng  1 , Salina Mohamed  2 , Mee Hoong See  3 , Faizah Harun  3 , Maznah Dahlui  4 , Ahmad Hatim Sulaiman  5 , Nor Zuraida Zainal  5 , Nur Aishah Taib  3 ; MyBCC Study group
Affiliations
Comparative Study

Anxiety, depression, perceived social support and quality of life in Malaysian breast cancer patients: a 1-year prospective study

Chong Guan Ng et al. Health Qual Life Outcomes. .

Abstract

Background: Depression and anxiety are common psychiatric morbidity among breast cancer patient. There is a lack of study examining the correlation between depression, anxiety and quality of life (QoL) with perceived social support (PSS) among breast cancer patients. This study aims to study the level of depression, anxiety, QoL and PSS among Malaysian breast cancer women over a period of 12 months and their associations at baseline, 6 and 12 months.

Methods: It is a 12 months prospective cohort study. Two hundred and twenty one female patients were included in the study. They were assessed at the time of diagnosis, 6 months and 12 month using Hospital Anxiety and Depression Scale (HADS), Quality-of-Life Questionnaire (QLQ-C30), Version 3.0 of the EORTC Study Group and Multidimensional Scale of Perceived Social Support (MSPSS). The information of age, ethnicity, types of treatment, and staging of cancer were collected.

Results: The HADS anxiety and depression subscales scores of the subjects were relatively low. The level of anxiety reduced significantly at 6 and 12 months (Baseline - 6 months, p = 0.002; Baseline - 12 months, p < 0.001). There were no changes in the level of depression over the study period. The global status of QoL and MSPSS scores were relatively high. Correlation between the global status of QoL and MSPSS for the study subjects was positive (Spearman's rho = 0.31-0.36). Global status of QoL and MSPSS scores were negatively correlated with anxiety and depression.

Conclusion: Malaysian breast cancer women had relatively better QoL with lower level of anxiety and depression. Perceived social support was an important factor for better QoL and low level of psychological distress. It reflects the importance of attention on activities that enhance and maintain the social support system for breast cancer patients.

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References

    1. National Cancer Registry Malaysia. Cancer statistics: Data and Figure. Kuala Lumpur, Malaysia: Ministry of Health Malaysia; 2006.
    1. Ries LAG, Melbert D, Krapcho M, Stinchcomb DG, Howlader N, Horner MJ, et al. (eds). SEER Cancer Statistics Review, 1975–2005, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/archive/csr/1975_2005/, based on November 2007 SEER data submission, posted to the SEER web site, 2008.
    1. O’Neil A, Stevenson CE, Williams ED, Mortimer D, Oldenburg B, Sanderson K. The health-related quality of life burden of co-morbid cardiovascular disease and major depressive disorder in Australia: findings from a population-based, cross-sectional study. Qual Life Res. 2013;22(1):37Y44. - PMC - PubMed
    1. Yusuf A, Hadi ISA, Mahamood Z, Ahmad Z, Keng SL. Quality of Life in Malay and Chinese Women Newly Diagnosed with Breast Cancer in Kelantan, Malaysia. Asian Pacific J Cancer Prev. 2013;14(1):435–440. doi: 10.7314/APJCP.2013.14.1.435. - DOI - PubMed
    1. Chui PL, Abdullah KL, Wong LP, Taib NA. Quality of Life in CAM and Non-CAM Users among Breast Cancer Patients during Chemotherapy in Malaysia. PLoS One. 2015;10(10):e0139952. doi: 10.1371/journal.pone.0139952. - DOI - PMC - PubMed

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