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. 2015 Jul-Aug;22(4):69-72.

Familial Adenomatous Polyposis-Associated Papillary Thyroid Cancer

Shahrun Niza Abdullah Suhaimi  1 , Nadzrin Nazri  1 , Mat Latar Nani Harlina  1 , Nurismah Md Isa  2 , Rohaizak Muhammad  1
Affiliations

Familial Adenomatous Polyposis-Associated Papillary Thyroid Cancer

Shahrun Niza Abdullah Suhaimi et al. Malays J Med Sci. 2015 Jul-Aug.

Abstract

Papillary thyroid carcinoma (PTC) associated with familial adenomatous polyposis (FAP) is rare. It is usually associated with the cribriform-morular variant of PTC, with unusual patterns on detailed histology examination. This variant is known to have a good prognosis. Papillary thyroid carcinoma associated with FAP commonly occurs in females in their 30s and rarely in the elderly. We report a case of a 69-year-old female presenting with thyroid swelling and a history of FAP.

Keywords: familial adenomatous polyposis; papillary thyroid carcinoma.

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Figures

Figure 1:
Figure 1:
Gross specimen of an enlarged right thyroid lobe and a normal left thyroid lobe.
Figure 2:
Figure 2:
Section shows malignant cells in cribriform pattern (H&E, X10).
Figure 3:
Figure 3:
Squamous morules with intranuclearpseudoinclusion and nuclear grooving (H&E, X40).
See this image and copyright information in PMC

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