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Case Reports
. 2015 Dec;5(6):524-527.
doi: 10.1212/CPJ.0000000000000192.

Systemic sarcoidosis presenting as Harlequin and Horner syndrome

Janice C Wong  1 , Jeffrey A Sparks  1 , Tracy J Doyle  1 , Vera A Paulson  1 , Tracey A Milligan  1 , Sashank Prasad  1
Affiliations
Case Reports

Systemic sarcoidosis presenting as Harlequin and Horner syndrome

Janice C Wong et al. Neurol Clin Pract. 2015 Dec.
No abstract available

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Figures

Figure
Figure. Harlequin and Horner syndromes in systemic sarcoidosis
(A) Harlequin syndrome was triggered after activity. (B) Left pupillary miosis was accentuated in darkness. (C) Apraclonidine test confirmed left-sided Horner syndrome with postapraclonidine left pupillary dilation. (D) Chest CT with evidence of peribronchovascular opacities, particularly in bilateral upper lobes. (E) On histology, the sacral core biopsy demonstrated diffuse intramedullary fibrosis with non-caseating granulomas (arrows), consistent with sarcoidosis. Large multinucleate giant cells (asterisks) are present within several of the granulomas.
See this image and copyright information in PMC

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