Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Dec;3(6):E547-51.
doi: 10.1055/s-0034-1392566. Epub 2015 Aug 3.

Iatrogenic perforation of esophagus successfully treated with Endoscopic Vacuum Therapy (EVT)

Affiliations

Iatrogenic perforation of esophagus successfully treated with Endoscopic Vacuum Therapy (EVT)

Gunnar Loske et al. Endosc Int Open. 2015 Dec.

Abstract

Background and study aims: Endoscopic Vacuum Therapy (EVT) has been reported as a novel treatment option for esophageal leakage. We present our results in the treatment of iatrogenic perforation with EVT in a case series of 10 patients.

Patients and methods: An open pore polyurethane drainage was placed either intracavitary through the perforation defect or intraluminal covering the defect zone. Application of vacuum suction with an electronic device (continuous negative pressure, -125 mmHg) resulted in defect closure and internal drainage.

Results: Esophageal perforations were located from the cricopharyngeus (4/10) to the esophagogastric junction (2/10). EVT was feasible in all patients. Eight patients were treated with intraluminal EVT, one with intracavitary EVT, and one with both types of treatments. All perforations (100 %) were healed in within a median of (3 - 7) days. No stenosis occurred, no complications were observed, and no additional operative treatment was necessary.

Conclusions: Our study suggests that intraluminal EVT will play an important role in endoscopic management of esophageal perforation.

PubMed Disclaimer

Conflict of interest statement

Competing interests: Gunnar Loske is a consultant for Lohmann & Rauscher GmbH & Co. KG. Tobias Schorsch, Christian Dahm, Eckhard Martens and Christian Müller declare that no conflict of interest exists.

Figures

Fig. 1 a
Fig. 1 a
Open pore polyurethane foam (PU) fixed at tip of drainage tube (T), endoscope (E), grasper (G), b Open pore drainage. Left: short polyurethane foam (PU) for intracavitary EVT; right: long PU for intraluminal EVT; endoscope (E); drainage tube (T).
Fig. 2 a
Fig. 2 a
Esophageal placement of open pore drainage (polyurethane foam [PU], suture [S], drainage tube [T], grasper [G]. b After 2 days of intracavitary EVT (wound edges [We] of perforation defect). c After 3 days of intraluminal EVT (wound edges [We] stick together). d 8 days after a 5-day treatment with EVT (erosion pattern has disappeared and a tiny scar [Sc] is the residuum of the perforation defect [esophageal Lumen {L}]).
Fig. 3
Fig. 3
Schematic for intraluminal EVT. a Open pore foam drainage has been inserted into the esophageal lumen. b After application of vacuum suction, the esophageal lumen collapses around and with the open pore foam.

References

    1. Carrott P W Jr, Low D E. Advances in the management of esophageal perforation. Thorac Surg Clin. 2011;21:541–555. - PubMed
    1. Schmidt S C, Strauch S, Rosch T. et al.Management of esophageal perforations. Surg Endosc. 2010;24:2809–2813. - PubMed
    1. Mennigen R, Senninger N, Laukoetter M G. Novel treatment options for perforations of the upper gastrointestinal tract: endoscopic vacuum therapy and over-the-scope clips. World J Gastroenterol. 2014;20:7767–7776. - PMC - PubMed
    1. Schaheen L, Blackmon S H, Nason K S. Optimal approach to the management of intrathoracic esophageal leak following esophagectomy: a systematic review. Am J Surg. 2014;208:536–543. - PMC - PubMed
    1. Schorsch T, Muller C, Loske G. Endoscopic vacuum therapy of anastomotic leakage and iatrogenic perforation in the esophagus. Surg Endosc. 2013;27:2040–2045. - PubMed