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Case Reports
. 2016 Jan 26;86(4):399-400.
doi: 10.1212/WNL.0000000000002312. Epub 2015 Dec 30.

Eculizumab-related progressive multifocal leukoencephalopathy

Emilio Gómez-Cibeira  1 , Yerko Ivanovic-Barbeito  1 , Eduardo Gutiérrez-Martínez  1 , Enrique Morales  1 , Manuel Abradelo  1 , Amaya Hilario  1 , Ana Ramos  1 , Juan Ruiz-Morales  1 , Alberto Villarejo-Galende  2
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Case Reports

Eculizumab-related progressive multifocal leukoencephalopathy

Emilio Gómez-Cibeira et al. Neurology. .
No abstract available

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Figures

Figure
Figure. Neuroimaging at onset and follow-up
MRI at presentation (A–C): fluid-attenuated inversion recovery images show hyperintense lesions in the dorsal pons, right middle cerebellar peduncle, and left cerebellum (A), and bihemispheric frontal white matter (B). Enhanced T1-weighted image shows multiples areas of punctate enhancement, especially in the right anterior frontal lobe and left frontal white matter. A previous surgery for right traumatic epidural hematoma can also be seen. The same sequences performed 4 months later (D–F) show residual pons lesions (D), reduction in size and number of the bihemispheric white matter hyperintensities (E), and resolution of contrast enhancement (F).
See this image and copyright information in PMC

References

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