Thoracoscopic lobectomy in a lung cancer patient with severe hemophilia: A case report

Abstract

Hemophilia is a hereditary disease with impaired blood coagulation due to a genetic deficiency of blood coagulation factors. Hemophilia often causes spontaneous life-threatening bleeding, so patients with hemophilia are often not suitable for any surgery that may cause iatrogenic bleeding and threaten the life of the patient. Therefore, surgery in lung cancer patients with hemophilia is extremely rare. The present study reported the case of a lung cancer patient with hemophilia who presented with a persistent cough. A mass was revealed by computed tomography and the patient underwent a successful thoracoscopic right lower lobectomy. The study discusses the patient's diagnosis and treatment options for hemophilia A and lung cancer, including indications for thoracoscopic lobectomy, pre-operative preparation and post-operative care, and other treatment options are discussed. The literature is also reviewed on this subject.

Keywords: coagulation factor VIII; hemophilia; lung cancer; thoracoscopy.

Figure 1.

Positron emission tomography-computed tomography showing a 3.0×2.0-cm mass (arrow) in the right lower lobe of the lung.