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. 1989 Sep;48(3 Suppl):S1-3.
doi: 10.1016/0003-4975(89)90615-2.

It will work: the first successful mitral valve replacement

N S Braunwald  1
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It will work: the first successful mitral valve replacement

N S Braunwald. Ann Thorac Surg. 1989 Sep.

Abstract

In 1959, a prosthetic mitral valve of flexible polyurethane with Teflon chordae tendineae was designed and fabricated. After a series of experiments in dogs carried out at the Clinic of Surgery at the National Heart Institute, on March 11, 1960, this valve was used as a total replacement of the mitral valve of a 44-year-old woman with mitral regurgitation. After an uneventful postoperative course, she was discharged from the hospital and did well thereafter, but died suddenly, presumably of an arrhythmia, 4 months after operation.

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