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Review
. 2015 Dec;3(21):322.
doi: 10.3978/j.issn.2305-5839.2015.12.23.

Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition)

Affiliations
Review

Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition)

Jun Guo et al. Ann Transl Med. 2015 Dec.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Flow chart of general rules and specific management of stage IV (skin melanoma). m, it is recommended that all patients with advanced melanoma receive gene detection before the initiation of treatment. Commercialized drugs targeting two well-studied targets, BRAF and CKIT, have been available; n, rapid progression refers that the tumor is expected to progress rapidly within 12 weeks, with LDH >1.5 times of the normal upper threshold and multiple organ metastases; or, the condition may be drudged by a clinician based on his/her clinical experiences; o, slow progression: refers to non-rapid progression; p, it is particularly recommended for patients with low PD-L1 expression; however, medication must be under the supervision of experienced physicians; q, cytotoxic drugs include dacarbazine, temozolomide, albumin-bound paclitaxel, paclitaxel, cisplatin/carboplatin, and fotemustine, and angiogenesis inhibitors include vascular endostatin and bevacizumab; r, high-dose IL-2 is not feasible in patients with organ dysfunction, poor physical performance, and/or non-treated or symptomatic brain metastases. IL-2 treatment may be considered in patients with small brain metastases and without edema (2B). However, medication must be under the supervision of experienced physicians; *, not licensed in China, for reference only, results of phase III clinical trials have been available in foreign countries.
Figure 2
Figure 2
COMS’s UM classification standards (226). In December 1990, the criteria of medium tumor height were decreased from 3 to 2.5 mm. COMS, Collaborative Ocular Melanoma Study; UM, uveal melanoma.

References

    1. Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015;136:E359-86. - PubMed
    1. Chinese Cancer Registry Annual Report 2014 (unpublished data).
    1. National Office of Tumor Prevention and Treatment & Ministry of Health Disease Prevention and Control Bureau. Chinese Cancer Registry Annual Report 2004. Beijing: Peking Union Medical College Press, 2008.
    1. Zhao P, Chen WQ, editors. Chinese Cancer Registry Annual Report 2008. Beijing: Military Medical Science Press, 2009.
    1. Zhao P, Chen WQ, editors. Chinese Cancer Registry Annual Report 2009. Beijing: Military Medical Science Press, 2010.