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Review
. 2015 Nov-Dec;28(4):290-2.
doi: 10.1590/S0102-6720201500040018.

URIC ACID AND TISSUE REPAIR

[Article in English, Portuguese]
Rodrigo Araldi Nery  1 , Barbara Stadler Kahlow  1 , Thelma L Skare  1 , Fernando Issamu Tabushi  1 , Adham do Amaral e Castro  1
Affiliations
Review

URIC ACID AND TISSUE REPAIR

[Article in English, Portuguese]
Rodrigo Araldi Nery et al. Arq Bras Cir Dig. 2015 Nov-Dec.

Abstract
in English, Portuguese

Uric acid, a metabolic product of purines, may exert a role in tissue healing. In this review we will explore its role as an alarm initiating the inflammatory process that is necessary for tissue repair, as a scavenger of oxygen free radicals, as a mobilizer of progenitor endothelial cells and as supporter of adaptive immune system.

O ácido úrico, um produto metabólico das purinas, pode exercer um papel na cicatrização de tecidos. Nesta revisão, será explorado o seu papel no alarme inicial do processo inflamatório que é necessário para o reparo tissular, bem como a sua atuação neutralizadora de radicais livres de oxigênio, mobilizadora de células endoteliais progenitoras e favorecedora da atuação do sistema imunológico adaptativo.

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Conflict of interest statement

Conflicts of interest: none

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