Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Mar;54(3):529-34.
doi: 10.1128/JCM.02771-15. Epub 2016 Jan 6.

The Problem of Carbapenemase-Producing-Carbapenem-Resistant-Enterobacteriaceae Detection

Joseph D Lutgring  1 , Brandi M Limbago  2
Affiliations
Review

The Problem of Carbapenemase-Producing-Carbapenem-Resistant-Enterobacteriaceae Detection

Joseph D Lutgring et al. J Clin Microbiol. 2016 Mar.

Abstract

The emergence and spread of carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) are a significant clinical and public health concern. Reliable detection of CP-CRE is the first step in combating this problem. There are both phenotypic and molecular methods available for CP-CRE detection. There is no single detection method that is ideal for all situations.

PubMed Disclaimer

References

    1. Peleg AY, Hooper DC. 2010. Hospital-acquired infections due to gram-negative bacteria. N Engl J Med 362:1804–1813. doi:10.1056/NEJMra0904124. - DOI - PMC - PubMed
    1. Guh AY, Limbago BM, Kallen AJ. 2014. Epidemiology and prevention of carbapenem-resistant Enterobacteriaceae in the United States. Expert Rev Anti Infect Ther 12:565–580. doi:10.1586/14787210.2014.902306. - DOI - PMC - PubMed
    1. Gupta N, Limbago BM, Patel JB, Kallen AJ. 2011. Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. Clin Infect Dis 53:60–67. doi:10.1093/cid/cir202. - DOI - PubMed
    1. Vasoo S, Barreto JN, Tosh PK. 2015. Emerging issues in gram-negative bacterial resistance: an update for the practicing clinician. Mayo Clin Proc 90:395–403. doi:10.1016/j.mayocp.2014.12.002. - DOI - PubMed
    1. Esterly JS, Wagner J, McLaughlin MM, Postelnick MJ, Qi C, Scheetz MH. 2012. Evaluation of clinical outcomes in patients with bloodstream infections due to gram-negative bacteria according to carbapenem MIC stratification. Antimicrob Agents Chemother 56:4885–4890. doi:10.1128/AAC.06365-11. - DOI - PMC - PubMed

MeSH terms