The SPRINT study: Outcome may be driven by difference in diuretic treatment demasking heart failure and study design may support systolic blood pressure target below 140 mmHg rather than below 120 mmHg

Affiliations

¹ a Department of Cardiology , University of Oslo, Ullevaal Hospital , Oslo , Norway ;
² b Department of Hypertension and Diabetology , Medical University of Gdansk , Gdansk , Poland ;
³ c Department of Medicine , University of Göteborg, Sahlgrenska Academy , Göteborg , Sweden ;
⁴ d IRCCS Istituto Auxologico Italiano, University of Milano-Bicocca , Milan , Italy.

Free article

Editorial

Sverre E Kjeldsen et al. Blood Press. 2016.

Free article

. 2016;25(2):63-6.

doi: 10.3109/08037051.2015.1130775. Epub 2016 Jan 8.

¹ a Department of Cardiology , University of Oslo, Ullevaal Hospital , Oslo , Norway ;
² b Department of Hypertension and Diabetology , Medical University of Gdansk , Gdansk , Poland ;
³ c Department of Medicine , University of Göteborg, Sahlgrenska Academy , Göteborg , Sweden ;
⁴ d IRCCS Istituto Auxologico Italiano, University of Milano-Bicocca , Milan , Italy.

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Comment on

The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: the Systolic Blood Pressure Intervention Trial (SPRINT).
Ambrosius WT, Sink KM, Foy CG, Berlowitz DR, Cheung AK, Cushman WC, Fine LJ, Goff DC Jr, Johnson KC, Killeen AA, Lewis CE, Oparil S, Reboussin DM, Rocco MV, Snyder JK, Williamson JD, Wright JT Jr, Whelton PK; SPRINT Study Research Group. Ambrosius WT, et al. Clin Trials. 2014 Oct;11(5):532-46. doi: 10.1177/1740774514537404. Epub 2014 Jun 5. Clin Trials. 2014. PMID: 24902920 Free PMC article. Clinical Trial.